1. Pale or Jaundiced Skin
Those who have B12 deficiency would often look pale and may develop a slight yellow tinge in their skin and sclera. This is because of the onset of jaundice and the reason for this is that their body is not producing enough red blood cells due to the deficiency of Vitamin B12.
Vitamin B12 plays an important role in producing the DNA required to produce red blood cells. If you do not have enough of this nutrient, the process involved in creating the cells will be deemed incomplete. The red blood cells are unable to divide hence they become bigger than normal. Their size prevents them from moving out of your bone marrow and entering the bloodstream. The lack of red blood cell in your blood results in pale skin.
Furthermore, because of their size, the cells are too fragile and they will end up breaking down. This will lead to the excess production of bilirubin, a substance is produced in the liver and has a slightly red or brownish color, which gives the skin a yellow tinge.
