SSRI/SNRIs for Fibromyalgia


There are many different kinds of treatments available for fibromyalgia (FMS) and chronic fatigue syndrome (CFS). Of all the treatments, the use of antidepressants raised many doubts. Many do not understand why medications that are intended to treat depression are being used to treat fibromyalgia or chronic fatigue syndrome.

However, there is an increasing number of evidence that proves that antidepressants are indeed effective in treating both FMS and CFS. This  is because antidepressants work by altering the way the neurotransmitters work in our brain and these are the same neurotransmitters that are involved in FMS and CFS, as well as major depressive disorders.

Antidepressants for Fibromyalgia

There are five main classes of antidepressants in the market. Below are the two types of antidepressants that are considered to be very effective in treating the symptoms of FMS:

  • Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs)
  • Selective Serotonin Reuptake Inhibitors (SSRIs)
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