Norepinephrine in Fibromyalgia


Low Norepinephrine Activity

Whenever doctors would say that there is a low norepinephrine activity in your body, they do not really mean that the amount of NE in your body is unusually low. Usually, for conditions that are linked to low norepinephrine activity, they would not know whether the issue has to do with the level itself. It may be because your body is just not using it efficiently. Or perhaps, it has something to do with the NE receptors. These are the chemical connecting points at the brain and nerve cells that are responsible for triggering the activity.

Regardless of the specific mechanism that is involved in the low NE activity, the symptoms, as well as the treatment, should be the same.

Symptoms and Conditions

Below are the symptoms of low NE activity:

  • Depression
  • Fatigued
  • Foggy brained
  • Lack of interest and arousal
  • Loss of alertness
  • Memory problems
  • Unmotivated

Below are some of the most common conditions that are associated with low NE activity:

  • Attention deficit disorders (ADD, ADHD)
  • Bipolar disorder (depression phase)
  • Chronic fatigue syndrome (CFS or ME/CFS)
  • Fibromyalgia (FMS)
  • Hypotension (very low blood pressure)
  • Major depressive disorder
  • Other mood disorders

Doctors are still looking into what causes low norepinephrine activity for these conditions.


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