What You Need To Know About Milnacipran (Savella) For Fibromyalgia


Side Effects of Milnacipran for Fibromyalgia

Milnacipran can result in many side effects. The most frequently observed side effect of Milnacipran is nausea. In addition, other side effects ranging from light to moderate side effects include:

  • gastrointestinal symptoms such as stomach discomfort, bloatedness, vomiting or constipation
  • feeling dizzy or drowsy
  • headaches
  • lethargy
  • hot flash or excessive perspiration
  • dry mouth
  • lack of appetite
  • sleeping difficulties
  • high blood pressure
  • swollen hands or feet
  • loss of interest in sex
  • weight fluctuations

Some people may also experience serious side effects. They include:

  • irregular heartbeat or palpitations
  • urine difficulty which may be accompanied with pain
  • abnormal excretion such as dark urine, black or blood red stools
  • vomit which resembles grounded coffee
  • jaundice
  • seizures
  • easily bruised or bleed

As with all type of antidepressants, one of the most dangerous side effect is the increased risk of suicidal thoughts especially in youths and young adults. Speak to your doctor immediately if you experience any of these serious side effects.


milnacipran for fibromyalgia

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  1. says: Kim

    This is another dangerous drug if you have a reaction to codine, morphine, lyrica, gabapentin, norspan, endone, OxyContin, pristiq, depression tablets you will have major reaction to these. I was on these for a week and very scary reactions.

  2. says: Mona Clark

    If this medication is so great, then why haven’t I read or heard about it in any of my fibromyalgia groups. Besides I can’t take it anyway. Side effects, don’t like the way seritonins, AB inhibitors, seizure meds make me feel, like a zombie. Let’s not for get depicote, slobbering out the mouth, that’s some nasty pills.

  3. says: Christine

    I won’t put that in my body either. The stigma of being on antidepressants leads to poor treatment in the ER. All pain you have is in your head. I’m a chronic pain patient wit fibromyalgia lupus RA and crps. I had a botched surgery. The minute they saw I was on an antidepressant and Lyrica I was not believed. I was left in agony for 5.5 months lost 90 pounds. All they offered me were warm compresses for the severe pain social workers and a psych consult. I had to travel out of town. Finally a surgeon took me seriously and found rotting organs. Oh yes. It took 3 surgeons to remove those organs. Since then I discontinued the antidepressants and Lyrica. I will not put that in my body ever again. This is the second time I’m ill treated by the medical system because o was on those drugs. Now I don’t care to ever seek medical treatment again. Btw I won my appeal and am waiting for the judgement. I was diagnostically overshadowed based on a mental health bias.

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