What You Need To Know About Milnacipran (Savella) For Fibromyalgia


How Does Milnacipran for Fibromyalgia Work?

Milnacipran, sold under the brand Savella, is the 3rd drug approved by FDA to treat fibromyalgia. Interestingly enough, the main use of the antidepressant is not for treating depression, which SNRI is commonly prescribed for.

Instead, it has been shown to be effective in reducing pain and fatigue and improving cognitive function. Nevertheless, fibromyalgia patients who also suffer from depression can also benefit from the antidepressant activity of the drug.

According to studies, 50 percent of those who took milnacipran showed promising results. This is significantly better than the 1 in every 10 successes from Lyrica’s pregabalin. Hence, milnacipran for fibromyalgia is considered an effective drug for treating its symptoms.


milnacipran for fibromyalgia

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  1. says: Kim

    This is another dangerous drug if you have a reaction to codine, morphine, lyrica, gabapentin, norspan, endone, OxyContin, pristiq, depression tablets you will have major reaction to these. I was on these for a week and very scary reactions.

  2. says: Mona Clark

    If this medication is so great, then why haven’t I read or heard about it in any of my fibromyalgia groups. Besides I can’t take it anyway. Side effects, don’t like the way seritonins, AB inhibitors, seizure meds make me feel, like a zombie. Let’s not for get depicote, slobbering out the mouth, that’s some nasty pills.

  3. says: Christine

    I won’t put that in my body either. The stigma of being on antidepressants leads to poor treatment in the ER. All pain you have is in your head. I’m a chronic pain patient wit fibromyalgia lupus RA and crps. I had a botched surgery. The minute they saw I was on an antidepressant and Lyrica I was not believed. I was left in agony for 5.5 months lost 90 pounds. All they offered me were warm compresses for the severe pain social workers and a psych consult. I had to travel out of town. Finally a surgeon took me seriously and found rotting organs. Oh yes. It took 3 surgeons to remove those organs. Since then I discontinued the antidepressants and Lyrica. I will not put that in my body ever again. This is the second time I’m ill treated by the medical system because o was on those drugs. Now I don’t care to ever seek medical treatment again. Btw I won my appeal and am waiting for the judgement. I was diagnostically overshadowed based on a mental health bias.

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