Another study related to Biological Psychiatry in 2017 suggests that having a disproportion between creatine and N-acetylaspartylglutamate leads to being at risk of having higher pain levels. Like other researches, this does not demonstrate the effectiveness of creatine to fight this illness. However, it provides a clear path for future discoveries.
Multiple studies propose that neurologic and mitochondrial disorders are part of the causes of fibromyalgia and chronic fatigue syndrome. Some of its effects may be eased by taking creatine supplements. These effects may include:
- Dysregulation of energy
- Ischemia due to lack of oxygen (anoxia or hypoxia)
- Oxidative stress
- Presence of toxins that are harmful to the tissues in the nervous system
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