Features of CSS
Abnormal levels or activities of neurotransmitters are often responsible for CSS pain and symptoms. The neurotransmitters that are involved in some of the CSS include the following:
- Serotonin
- Norepinephrine
- GABA and glutamate
- Dopamine
The pain that a patient would feel in CSS is a result of a couple of abnormal pain types known as hyperalgesia and allodynia.
Hyperalgesia will follow same feeling of pain from things that all people will find painful, such as when having a toothache or broken limb, but will make it even worse. This abnormal pain type is also being referred to as something that turns up the volume of pain. Because of hyperalgesia, injuries, surgeries and other origins of pain can become debilitating.
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