There is no denying of the fact that stress and anxiety is not good for any human, needless to say a fibromyalgia patient. Stress affects physical as well as mental health of an individual. Fibro flares becomes worse when you are undergoing any stress and depression. It is more noticeable when you are going through excessive stress due to work, financial constraints, disruptive personal relationships and so on. Prolonged stress can weaken your immune system making you more susceptible to infections, toxins and allergies.